Ropivacaine hydrochloride
- Product Name
- Ropivacaine hydrochloride
- CAS No.
- 132112-35-7
- Chemical Name
- Ropivacaine hydrochloride
- Synonyms
- ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono);Ropivacaine HCl hydrate
- CBNumber
- CB0369811
- Molecular Formula
- C17H26N2O.ClH.H2O
- Formula Weight
- 328.88
- MOL File
- 132112-35-7.mol
Ropivacaine hydrochloride Property
- Melting point:
- 267-269°C
- alpha
- D20 -7.28° (c = 2 in water)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble5mg/mL, clear
- form
- powder
- color
- white to off-white
- optical activity
- [α]/D -9 to -12, c = 1 in methanol
- InChIKey
- VSHFRHVKMYGBJL-CKUXDGONSA-N
- CAS DataBase Reference
- 132112-35-7(CAS DataBase Reference)
Safety
- Hazard Codes
- T,Xi
- Risk Statements
- 26/27/28-41
- Safety Statements
- 22-36/37/39-45-39-26
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- HS Code
- 2933399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R0283
- Product name
- Ropivacaine hydrochloride monohydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $84.1
- Updated
- 2024/03/01
- Product number
- PHR2303
- Product name
- Ropivacaine hydrochloride
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 500MG
- Price
- $253
- Updated
- 2024/03/01
- Product number
- 1605500
- Product name
- Ropivacaine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $436
- Updated
- 2024/03/01
- Product number
- 21422
- Product name
- Ropivacaine (hydrochloride hydrate)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $63
- Updated
- 2024/03/01
- Product number
- 21422
- Product name
- Ropivacaine (hydrochloride hydrate)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $117
- Updated
- 2024/03/01
Ropivacaine hydrochloride Chemical Properties,Usage,Production
Description
(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
Chemical Properties
White Solid
Uses
Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.
Uses
Anesthetic (local).
Definition
ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.
General Description
Ropivacaine has lidocaine-related structure with tertiary amine side chains.?It is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom.
Biochem/physiol Actions
Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.
Ropivacaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Ropivacaine hydrochloride Suppliers
View Lastest Price from Ropivacaine hydrochloride manufacturers
- Product
- Ropivacaine Hcl 132112-35-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 0.98
- Supply Ability
- 1000
- Release date
- 2024-04-26
- Product
- Mepivacaine hydrochloride 132112-35-7
- Price
- US $1.00/mg
- Min. Order
- 1000mg
- Purity
- 99
- Supply Ability
- 5ton/month
- Release date
- 2022-02-17
- Product
- Ropivacaine hydrochloride 132112-35-7
- Price
- US $1.00/mg
- Min. Order
- 1000mg
- Purity
- 99
- Supply Ability
- 5ton/month
- Release date
- 2022-02-18